In the 21st century, higher education faces the dual challenge of delivering academic excellence while equipping students with essential life and career skills, including digital literacy, critical thinking, and collaboration. Music students undergo intensive training, navigate performance anxiety, and encounter peer-related social pressures, all of which significantly impact their well-being. The goal is to propose guidelines that promote student well-being in alignment with contemporary learning contexts. A qualitative design was employed, using semi-structured interviews and focus group discussions. Participants included fourth-year undergraduate music students and faculty members.The research findings reveal that student well-being is interconnected across four dimensions: physical, emotional, social, and intellectual. Students emphasize aspects of well-being that directly influence their learning, practice, and musical performance, including continuous attention to physical health and emotional regulation. These factors contribute to effective collaboration and positive social interactions. While intellectual well-being highlights how music learning shapes diverse cognitive processes and individual perspectives. In terms of 21st-century skills, encompassing learning skills, literacy skills, life and career skills, as well as core subjects and cross-curricular competencies, students expressed both shared and differing views depending on their fields of study. These differences reflect a variety of perspectives on how such skills can be adapted to personal contexts and applied to future professional careers as effectively as possible. Faculty perspectives highlighted three priorities: (1) enhanced institutional support through dedicated well-being services; (2) curriculum relevance that balances core musical competencies with creativity, AI integration, and digital literacy; and (3) integrative strategies that embed well-being into curriculum design, offer flexibility across academic tracks, and promote psychologically safe learning environments. concludes that student well-being and 21st-century learning are fundamentally interconnected. Holistic support, addressing physical, emotional, social, and cognitive dimensions, is essential not only for individual resilience but also for long-term success. To respond to the demands of a rapidly evolving world, music education institutions must enact structural, curricular, and cultural reforms. Embedding well-being into the core of music education through student-centered, psychologically safe, and adaptable learning environments will empower learners to thrive